disease 1,940 words KG: ent-dise-cb6dddde 2026-03-24
kind:diseasesection:diseasesstate:published
Contents

Microcephaly

Disease Info
ASPM-related microcephalyMutations in ASPM gene
CENPJ-related microcephalySee CENPJ
WDR62-related microcephalySee WDR62
Spindle orientationProper orientation determines whether progenitor cells divide symmetrically (expanding the pool) or asymmetrically (producing neurons)
Centrosome functionCritical for proper chromosome segregation
DNA damage responseGenomic stability affects neural progenitor survival
Cell cycle regulationAbnormal cell cycle kinetics reduce proliferation
DatabasesOMIMOrphanetClinicalTrialsPubMed

Knowledge Graph