Scientific World Model

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

17,496 pages — genes, proteins, mechanisms, therapeutics, and more

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

All (17,496)🧬 gene (3,869)🔬 cell (3,397)🔬 protein (3,107)⚙️ mechanism (1,789)💊 therapeutic (1,028)🏢 company (643)🏥 disease (498)🧪 clinical (392)🏛️ institution (308)👤 researcher (214)💡 idea (200)↪️ redirect (185)📊 biomarker (182)🧫 experiment (161) general (151)🔧 technology (151) ai_tool (139) entity (114)
Showing 1–12 of 12 pages matching "TDP-43"

⚙️ TDP-43 ProteinopathyKG

mechanism · 4,112 words · 17 hyp40 ana31 exp

⚙️ TDP-43 Proteinopathy in Amyotrophic Lateral SclerosisKG

mechanism · 3,471 words · 15 hyp47 ana33 exp

⚙️ tdp-43-fus-rna-proteinopathy-comparisonKG

mechanism · 2,886 words · 13 hyp43 ana33 exp

⚙️ VCP→TDP-43→ALS/FTD Causal ChainKG

mechanism · 2,601 words · 10 hyp43 ana37 exp

⚙️ AD-FTD Tau-TDP-43 Overlap: Mechanism ComparisonKG

mechanism · 2,557 words · 21 hyp41 ana22 exp

⚙️ TDP-43 Pathology in Corticobasal SyndromeKG

mechanism · 2,095 words · 5 hyp39 ana29 exp

⚙️ TDP-43 Co-pathology in Corticobasal SyndromeKG

mechanism · 1,943 words · 5 hyp41 ana31 exp

⚙️ TDP-43 Proteinopathy in ALSKG

mechanism · 1,751 words · 12 hyp47 ana52 exp

⚙️ TDP-43 RNA Granule PathwayKG

mechanism · 1,601 words · 31 hyp47 ana39 exp

⚙️ Cryptic Exon Splicing in TDP-43 ProteinopathyKG

mechanism · 1,514 words · 6 hyp33 ana3 exp

⚙️ TDP-43 DNA Repair Mechanism in ALS and DementiaKG

mechanism · 1,318 words · 13 hyp47 ana49 exp

⚙️ TDP-43 Pathology Reversibility in ALSKG

mechanism · 1,312 words · 9 hyp47 ana50 exp

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