Contents

VCP→TDP-43→ALS/FTD Causal Chain

🔬 Protein Info

Gene Symbol	ent-gene-9a7e7e49
Function	VCP in Protein Quality Control
N-terminal domain	Adapter protein binding, substrate recognition
D1 domain	First ATPase domain, hexamer assembly
D2 domain	Second ATPase domain, major catalytic activity
C-terminal domain	Regulatory, substrate interaction
KG Connections	9 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING