Scientific World Model

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

17,496 pages — genes, proteins, mechanisms, therapeutics, and more

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

All (17,496)🧬 gene (3,869)🔬 cell (3,397)🔬 protein (3,107)⚙️ mechanism (1,789)💊 therapeutic (1,028)🏢 company (643)🏥 disease (498)🧪 clinical (392)🏛️ institution (308)👤 researcher (214)💡 idea (200)↪️ redirect (185)📊 biomarker (182)🧫 experiment (161) general (151)🔧 technology (151) ai_tool (139) entity (114)
Showing 1–22 of 22 pages matching "amyloid-beta"

⚙️ amyloid-beta-metalloproteinasesKG

mechanism · 4,656 words · 180 hyp67 ana16 exp

⚙️ Amyloid-Beta Aggregation and Plaque FormationKG

mechanism · 3,820 words · 181 hyp67 ana23 exp

⚙️ Amyloid-beta Fibril Formation PathwayKG

mechanism · 3,761 words · 189 hyp67 ana25 exp

📊 Beta-Amyloid 42/40 Ratio - BiomarkerKG

biomarker · 3,667 words · 17 hyp11 ana18 exp

⚙️ Amyloid-beta Cellular Uptake PathwayKG

mechanism · 3,408 words · 198 hyp68 ana29 exp

🔀 APP→Amyloid-beta→Plaque→Alzheimer's Disease Causal ChainKG

pathway · 3,076 words · 52 hyp55 ana95 exp

🔬 Amyloid-Beta (Aβ)KG

protein · 3,049 words · 47 hyp11 ana16 exp

⚙️ Amyloid-beta Oligomerization PathwayKG

mechanism · 2,599 words · 190 hyp67 ana18 exp

⚙️ amyloid-beta-cellular-uptakeKG

mechanism · 2,594 words · 189 hyp68 ana29 exp

⚙️ LRP1-Mediated Amyloid-Beta Clearance in NeurodegenerationKG

mechanism · 2,102 words · 295 hyp57 ana85 exp

⚙️ Amyloid-beta Fibril FormationKG

mechanism · 2,012 words · 180 hyp67 ana17 exp

Alzheimer's Disease Neuropathology is Defined by the Accumulation of Pathological Amyloid-Beta in the Form of Senile Plaques and Dystrophic Neurites, and Phosphorylated Tau Neurofibrillary TanglesKG

hypothesis · 1,801 words · 45 hyp32 ana69 exp

🔬 Amyloid-Beta Metabolism in Cortical NeuronsKG

cell · 1,655 words · 180 hyp65 ana24 exp

⚙️ Amyloid-beta Trans-synaptic Spread PathwayKG

mechanism · 1,485 words · 242 hyp68 ana19 exp

⚙️ Amyloid-Beta Clearance Therapeutic PathwaysKG

mechanism · 1,396 words · 191 hyp75 ana25 exp

⚙️ Amyloid-beta Degradation PathwaysKG

mechanism · 1,361 words · 186 hyp67 ana17 exp

📊 Amyloid Beta 40 (Aβ40) - BiomarkerKG

biomarker · 1,357 words · 176 hyp61 ana28 exp

🔬 Amyloid-Beta Accumulating NeuronsKG

cell · 1,109 words · 178 hyp65 ana22 exp

⚙️ APP Processing and Amyloid-Beta ProductionKG

mechanism · 1,051 words · 18 hyp43 ana37 exp

🔬 Amyloid-Beta-Exposed NeuronsKG

cell · 803 words · 176 hyp65 ana24 exp

🔬 Amyloid-beta ProteinKG

protein · 592 words · 24 hyp26 ana35 exp

🔬 Amyloid-Beta-Exposed NeuronsKG

cell · 544 words · 177 hyp65 ana24 exp

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