Scientific World Model

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

17,471 pages — genes, proteins, mechanisms, therapeutics, and more

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

All (17,471)🧬 gene (3,869)🔬 cell (3,397)🔬 protein (3,107)⚙️ mechanism (1,789)💊 therapeutic (1,028)🏢 company (643)🏥 disease (496)🧪 clinical (392)🏛️ institution (308)👤 researcher (214)💡 idea (200)↪️ redirect (185)📊 biomarker (182)🧫 experiment (161) general (151)🔧 technology (151) ai_tool (141) entity (113)
Showing 1–50 of 69 pages matching "meta"

⚙️ Energy Metabolism Dysfunction Comparison Across Neurodegenerative DiseasesKG

mechanism · 4,869 words · 38 hyp41 ana5 exp

⚙️ amyloid-beta-metalloproteinasesKG

mechanism · 4,656 words · 181 hyp65 ana16 exp

⚙️ RNA Metabolism Dysregulation in Alzheimer's DiseaseKG

mechanism · 4,024 words · 90 hyp61 ana167 exp

⚙️ metabolic-dysfunction-neurodegenerationKG

mechanism · 3,868 words · 293 hyp60 ana58 exp

⚙️ Lipid Metabolism Dysfunction Comparison — AD/PD/ALS/FTD/HDKG

mechanism · 3,831 words · 45 hyp41 ana46 exp

⚙️ Metabolomic Alterations in PSPKG

mechanism · 3,804 words · 6 hyp37 ana8 exp

⚙️ Metal Homeostasis Dysfunction Comparison Across Neurodegenerative DiseasesKG

mechanism · 3,711 words · 17 hyp40 ana3 exp

⚙️ Hydrogen Peroxide Metabolism PathwayKG

mechanism · 3,544 words · 24 hyp41 ana13 exp

⚙️ Lipid Metabolism Dysregulation in NeurodegenerationKG

mechanism · 3,499 words · 297 hyp60 ana71 exp

⚙️ Metabolic Dysfunction in Corticobasal DegenerationKG

mechanism · 3,345 words · 53 hyp60 ana5 exp

⚙️ Astrocyte Metabolic Enhancement Therapy for PDKG

mechanism · 3,337 words · 179 hyp67 ana21 exp

⚙️ Oligodendrocyte-Neuron Metabolic Support Pathway in NeurodegenerationKG

mechanism · 3,239 words · 302 hyp60 ana55 exp

⚙️ ALS RNA Metabolism and Proteostasis FailureKG

mechanism · 3,179 words · 27 hyp60 ana59 exp

⚙️ Astrocyte-Neuron Metabolic Coupling PathwayKG

mechanism · 3,060 words · 160 hyp65 ana17 exp

⚙️ Glutathione Metabolism PathwayKG

mechanism · 3,056 words · 48 hyp50 ana3 exp

⚙️ NAD+ Metabolism in NeurodegenerationKG

mechanism · 3,033 words · 294 hyp60 ana75 exp

⚙️ Energy Metabolism in NeurodegenerationKG

mechanism · 3,011 words · 292 hyp58 ana62 exp

⚙️ Metabolic Dysfunction in Alzheimer's DiseaseKG

mechanism · 3,005 words · 108 hyp71 ana59 exp

⚙️ iron-metabolism-neurodegenerationKG

mechanism · 2,926 words · 320 hyp61 ana56 exp

⚙️ one-carbon-metabolism-neurodegenerationKG

mechanism · 2,848 words · 281 hyp57 ana54 exp

⚙️ Sulfatide Metabolism in NeurodegenerationKG

mechanism · 2,842 words · 283 hyp57 ana65 exp

⚙️ Parkinson's Disease MetabolismKG

mechanism · 2,818 words · 18 hyp47 ana63 exp

⚙️ Metal Dyshomeostasis in Neurodegenerative Disease ComparisonKG

mechanism · 2,805 words · 5 hyp43 ana1 exp

⚙️ Microglia-Neuron Metabolic Cross-Talk in NeurodegenerationKG

mechanism · 2,668 words · 347 hyp74 ana78 exp

⚙️ Metabolic Dysfunction in 4R-TauopathiesKG

mechanism · 2,556 words · 55 hyp58 ana5 exp

⚙️ PKM2 Metabolic Dysregulation in Alzheimer's DiseaseKG

mechanism · 2,443 words · 83 hyp54 ana51 exp

⚙️ Serum Amino Acid Biomarkers for Brain HypometabolismKG

mechanism · 2,337 words · 22 hyp41 ana14 exp

⚙️ RNA Metabolism in NeurodegenerationKG

mechanism · 2,301 words · 288 hyp61 ana169 exp

⚙️ metal-dyshomeostasisKG

mechanism · 2,282 words · 6 hyp32 ana1 exp

⚙️ Metal Ion Dyshomeostasis in Corticobasal SyndromeKG

mechanism · 2,238 words · 8 hyp34 ana1 exp

⚙️ Prion Protein Metabolism in NeurodegenerationKG

mechanism · 2,230 words · 284 hyp55 ana55 exp

⚙️ Metal Homeostasis Dysregulation in 4R-TauopathiesKG

mechanism · 2,143 words · 14 hyp35 ana6 exp

⚙️ Metal Ion Homeostasis in Parkinson's DiseaseKG

mechanism · 2,076 words · 6 hyp40 ana62 exp

⚙️ RNA Metabolism in Alzheimer's DiseaseKG

mechanism · 2,071 words · 63 hyp66 ana169 exp

⚙️ NAD+ Metabolism Pathway in NeurodegenerationKG

mechanism · 2,062 words · 295 hyp60 ana72 exp

⚙️ Dopamine Metabolism in PDKG

mechanism · 2,046 words · 118 hyp60 ana4 exp

⚙️ Sphingolipid Metabolism Dysregulation in 4R-TauopathiesKG

mechanism · 1,999 words · 42 hyp41 ana18 exp

⚙️ Sphingolipid Metabolism in NeurodegenerationKG

mechanism · 1,980 words · 291 hyp56 ana65 exp

⚙️ Metal Ion Toxicity in NeurodegenerationKG

mechanism · 1,926 words · 280 hyp52 ana54 exp

⚙️ RNA Metabolism Dysfunction in Corticobasal SyndromeKG

mechanism · 1,903 words · 29 hyp46 ana119 exp

⚙️ Plasmalogen Metabolism in NeurodegenerationKG

mechanism · 1,852 words · 281 hyp57 ana55 exp

⚙️ Metal Homeostasis Dysregulation in NeurodegenerationKG

mechanism · 1,839 words · 283 hyp53 ana57 exp

⚙️ Polyamine Metabolism Pathway in NeurodegenerationKG

mechanism · 1,767 words · 294 hyp58 ana60 exp

⚙️ Neuroimmune Checkpoint-Metal-Oxidative Stress Convergence SynthesisKG

mechanism · 1,752 words · 34 hyp40 ana19 exp

⚙️ Metal Ion-Synuclein-Mitochondria (MISM) Axis in Parkinson's DiseaseKG

mechanism · 1,721 words · 40 hyp45 ana63 exp

⚙️ RNA Metabolism Dysregulation in 4R-TauopathiesKG

mechanism · 1,707 words · 24 hyp45 ana119 exp

⚙️ Metal Homeostasis in NeurodegenerationKG

mechanism · 1,682 words · 281 hyp56 ana55 exp

⚙️ Microbiome-Metabolic-Inflammation Triad in AD: Experimental ProtocolKG

mechanism · 1,671 words · 32 hyp44 ana6 exp

⚙️ Metabolic-Epigenetic Axis in Neurodegeneration SynthesisKG

mechanism · 1,658 words · 298 hyp61 ana61 exp

⚙️ PSP Oligodendrocyte Dysfunction and Iron MetabolismKG

mechanism · 1,599 words · 18 hyp39 ana22 exp

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