Scientific World Model

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

17,471 pages — genes, proteins, mechanisms, therapeutics, and more

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

All (17,471)🧬 gene (3,869)🔬 cell (3,397)🔬 protein (3,107)⚙️ mechanism (1,789)💊 therapeutic (1,028)🏢 company (643)🏥 disease (496)🧪 clinical (392)🏛️ institution (308)👤 researcher (214)💡 idea (200)↪️ redirect (185)📊 biomarker (182)🧫 experiment (161) general (151)🔧 technology (151) ai_tool (141) entity (113)
Showing 1–37 of 37 pages matching "amyloid"

⚙️ amyloid-beta-metalloproteinasesKG

mechanism · 4,656 words · 181 hyp65 ana16 exp

⚙️ Amyloid Cascade PathwayKG

mechanism · 4,149 words · 200 hyp65 ana25 exp

⚙️ Amyloid-Beta Aggregation and Plaque FormationKG

mechanism · 3,820 words · 184 hyp65 ana23 exp

⚙️ Amyloid-beta Fibril Formation PathwayKG

mechanism · 3,761 words · 191 hyp65 ana22 exp

⚙️ Amyloid-beta Cellular Uptake PathwayKG

mechanism · 3,408 words · 200 hyp66 ana26 exp

⚙️ brain-age-gap-amyloid-adKG

mechanism · 2,685 words · 213 hyp66 ana28 exp

⚙️ Cerebral Amyloid Angiopathy Pathway in NeurodegenerationKG

mechanism · 2,677 words · 293 hyp55 ana69 exp

⚙️ Enzymes of Physiological Amyloidogenesis in NeurodegenerationKG

mechanism · 2,636 words · 278 hyp52 ana66 exp

⚙️ Amyloid-beta Oligomerization PathwayKG

mechanism · 2,599 words · 192 hyp65 ana18 exp

⚙️ amyloid-beta-cellular-uptakeKG

mechanism · 2,594 words · 194 hyp66 ana29 exp

⚙️ amyloid-cascade-hypothesisKG

mechanism · 2,586 words · 194 hyp65 ana20 exp

⚙️ amyloid-cascade-pathwayKG

mechanism · 2,447 words · 203 hyp65 ana30 exp

⚙️ Acarbose Modulation of Alpha-Synuclein Amyloid FibrillationKG

mechanism · 2,373 words · 23 hyp48 ana12 exp

⚙️ Amyloid-Tau Synergistic Interaction HypothesisKG

mechanism · 2,372 words · 182 hyp65 ana18 exp

⚙️ Diffuse Amyloid Deposits in Alzheimer's DiseaseKG

mechanism · 2,321 words · 43 hyp24 ana58 exp

⚙️ Cerebral Amyloid Angiopathy: Mechanism and NeurodegenerationKG

mechanism · 2,287 words · 291 hyp55 ana69 exp

⚙️ amyloid-hypothesisKG

mechanism · 2,274 words · 184 hyp65 ana17 exp

⚙️ Amyloid vs Tau-First HypothesisKG

mechanism · 2,141 words · 187 hyp66 ana27 exp

⚙️ LRP1-Mediated Amyloid-Beta Clearance in NeurodegenerationKG

mechanism · 2,102 words · 298 hyp57 ana85 exp

⚙️ Amyloid-beta Fibril FormationKG

mechanism · 2,012 words · 180 hyp65 ana17 exp

⚙️ Amyloid Conformational StrainsKG

mechanism · 1,988 words · 188 hyp66 ana25 exp

⚙️ Tumor-Derived Cystatin C Enables Amyloid ClearanceKG

mechanism · 1,873 words · 153 hyp67 ana19 exp

⚙️ Anti-Amyloid Therapeutics: Successes, Failures, and Lessons LearnedKG

mechanism · 1,865 words · 125 hyp64 ana33 exp

⚙️ Amyloid-Tau Synergistic Interaction Hypothesis in Alzheimer's DiseaseKG

mechanism · 1,774 words · 211 hyp73 ana72 exp

⚙️ Amyloid Clearance MechanismsKG

mechanism · 1,665 words · 48 hyp46 ana28 exp

⚙️ BACE1 Amyloidogenic Cleavage PathwayKG

mechanism · 1,517 words · 18 hyp38 ana18 exp

⚙️ Amyloid-beta Trans-synaptic Spread PathwayKG

mechanism · 1,485 words · 242 hyp66 ana19 exp

⚙️ Amyloid-Beta Clearance Therapeutic PathwaysKG

mechanism · 1,396 words · 195 hyp73 ana25 exp

⚙️ Amyloid-beta Degradation PathwaysKG

mechanism · 1,361 words · 187 hyp65 ana17 exp

⚙️ CLU-Clusterin Amyloid Clearance Dysfunction AD Causal ChainKG

mechanism · 1,306 words · 38 hyp46 ana25 exp

⚙️ Cerebral Amyloid Angiopathy in NeurodegenerationKG

mechanism · 1,235 words · 289 hyp59 ana69 exp

⚙️ Modified Amyloid Cascade HypothesisKG

mechanism · 1,098 words · 27 hyp40 ana13 exp

⚙️ APP Processing and Amyloid-Beta ProductionKG

mechanism · 1,051 words · 21 hyp43 ana37 exp

⚙️ Amyloid vs Tau-First Hypothesis in Alzheimer's DiseaseKG

mechanism · 910 words · 204 hyp74 ana67 exp

⚙️ Amyloid Oligomers in NeurodegenerationKG

mechanism · 855 words · 335 hyp64 ana77 exp

⚙️ APP Amyloid Pathway in Alzheimer's DiseaseKG

mechanism · 807 words · 53 hyp59 ana84 exp

⚙️ amyloid-pathologyKG

mechanism · 758 words · 74 hyp66 ana13 exp

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