Contents

CLU-Clusterin Amyloid Clearance Dysfunction AD Causal Chain

🔬 Protein Info

Gene Symbol	CLU
Full Name	Clusterin Amyloid Clearance Dysfunction AD Causal Chain
Aliases	Page for CLU Gene
Chromosome	8p21.1
Function	is a gene located on chromosome 8p21.
Primary Expression	Hippocampus, Cortex, Basal ganglia, Cerebellum
Exons	9
Pathways	Astrocyte Reactivity, Blood-Brain Barrier, Camp Signaling, Complement, Dysbiosis
UniProt ID	P10909
NCBI Gene ID	1115
Ensembl ID	ENSG00000120885
OMIM	185551
GeneCards	CLU
Human Protein Atlas	CLU
European ancestry	rs11136000-T allele frequency ~57% (protective)
Associated Diseases	ALS, ALZHEIMER'S DISEASE, Aging, Alzheimer, Alzheimer disease
Interactions	PPARGC1A, BAX, LC3, PPARG, C1Q, TREM2
KG Connections	1093 knowledge graph edges
Databases	GeneCards HPA STRING

Knowledge Graph