Scientific World Model

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

17,471 pages — genes, proteins, mechanisms, therapeutics, and more

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

All (17,471)🧬 gene (3,869)🔬 cell (3,397)🔬 protein (3,107)⚙️ mechanism (1,789)💊 therapeutic (1,028)🏢 company (643)🏥 disease (496)🧪 clinical (392)🏛️ institution (308)👤 researcher (214)💡 idea (200)↪️ redirect (185)📊 biomarker (182)🧫 experiment (161) general (151)🔧 technology (151) ai_tool (141) entity (113)
Showing 1–50 of 82 pages matching "app"

⚙️ ALS Failed Approaches AnalysisKG

mechanism · 4,973 words · 8 hyp58 ana58 exp

🏥 APP Flemish Mutation (APP Flemish)KG

disease · 3,868 words · 6 hyp6 ana25 exp

💊 Nanomedicine Approaches to Alzheimer's DiseaseKG

therapeutic · 3,864 words · 56 hyp29 ana54 exp

⚙️ NF-κB Signaling Pathway in NeurodegenerationKG

mechanism · 3,689 words · 297 hyp57 ana62 exp

🧬 KRIT1 — Krev Interaction Trapped 1 (CCM1)KG

gene · 3,621 words · 3 hyp1 ana

⚙️ AD Biomarker-to-Mechanism MappingKG

mechanism · 3,567 words · 21 hyp38 ana8 exp

Amyloid Precursor Protein (APP)KG

entity · 3,485 words · 187 hyp60 ana23 exp

⚙️ AD Therapeutic Approaches Ranked ScorecardKG

mechanism · 3,392 words · 32 hyp52 ana8 exp

⚙️ Golgi Apparatus Stress Comparison Across Neurodegenerative DiseasesKG

mechanism · 3,286 words · 32 hyp39 ana2 exp

⚙️ ALS Biomarker-to-Mechanism MappingKG

mechanism · 3,189 words · 15 hyp52 ana61 exp

🧬 RNASEK — Ribonuclease KappaKG

gene · 3,161 words · 20 hyp3 ana5 exp

🔀 APP→Amyloid-beta→Plaque→Alzheimer's Disease Causal ChainKG

pathway · 3,076 words · 60 hyp55 ana95 exp

🧬 DCPS - Decapping EnzymeKG

gene · 3,039 words · 11 hyp4 ana

⚙️ [AD](/diseases/alzheimers-disease) Failed Approaches AnalysisKG

mechanism · 3,014 words · 22 hyp59 ana4 exp

⚙️ PD Failed Approaches AutopsyKG

mechanism · 2,975 words · 4 hyp43 ana4 exp

🏛️ cureapp-inc

institution · 2,959 words · 6 hyp2 ana

⚙️ MSA Treatment Approaches and Emerging TherapiesKG

mechanism · 2,899 words · 12 hyp36 ana9 exp

AAIC 2026: Combination Therapy and Multi-Target Approaches in Alzheimer's DiseaseKG

event · 2,892 words · 63 hyp34 ana48 exp

🔬 APP ProteinKG

protein · 2,826 words · 136 hyp48 ana24 exp

💊 PD Therapeutic Approaches ScorecardKG

therapeutic · 2,591 words · 22 hyp22 ana11 exp

🧬 APP — Amyloid Precursor ProteinKG

gene · 2,551 words · 186 hyp42 ana24 exp

💊 Combination Therapy Approaches in Neurodegenerative DiseaseKG

therapeutic · 2,545 words · 75 hyp43 ana12 exp

⚙️ Therapeutic Synergy and Combination Approach RankingsKG

mechanism · 2,472 words · 29 hyp53 ana11 exp

⚙️ APP-BACE1-Fe65 ComplexKG

mechanism · 2,240 words · 16 hyp37 ana24 exp

⚙️ Golgi Apparatus Dysfunction PathwayKG

mechanism · 2,160 words · 24 hyp43 ana1 exp

📊 Soluble Amyloid Precursor Protein Beta (sAPPβ)KG

biomarker · 2,123 words · 25 hyp16 ana15 exp

🔬 DCPS Protein (Decapping Scavenger)KG

protein · 2,116 words · 8 hyp6 ana2 exp

🏥 APP Dutch Mutation (APP Dutch)KG

disease · 2,054 words · 14 hyp16 ana24 exp

💊 Section 113: Emerging Gene Therapy Approaches for CBS/PSPKG

therapeutic · 2,048 words · 67 hyp26 ana20 exp

🏢 Apple Inc.KG

company · 1,998 words · 3 hyp1 ana

💊 AD Therapeutic Approaches Scorecard - 28 Approaches RankedKG

therapeutic · 1,953 words · 26 hyp27 ana7 exp

⚙️ HD Therapeutic Approaches Ranked ScorecardKG

mechanism · 1,890 words · 8 hyp47 ana9 exp

APP Swedish Mutation (APPswe)KG

mutation · 1,889 words · 13 hyp6 ana24 exp

⚙️ PD Biomarker-to-Mechanism MappingKG

mechanism · 1,875 words · 15 hyp34 ana3 exp

⚙️ Rehabilitation and Management of Progressive Supranuclear PalsyKG

mechanism · 1,848 words · 3 hyp35 ana23 exp

💊 Precision Medicine Approaches for NeurodegenerationKG

therapeutic · 1,833 words · 296 hyp52 ana64 exp

📊 AD Biomarker-to-Mechanism Mapping - Biomarker GuideKG

biomarker · 1,823 words · 35 hyp9 ana19 exp

💊 Section 241: Advanced Gene Therapy and CRISPR Approaches in CBS/PSPKG

therapeutic · 1,782 words · 69 hyp30 ana20 exp

⚙️ Biotech Company-Mechanism Pipeline MappingKG

mechanism · 1,730 words · 10 hyp35 ana6 exp

⚙️ APP/PS1 Double Transgenic Mouse ModelKG

mechanism · 1,702 words · 28 hyp55 ana24 exp

⚙️ SORL1→APP Trafficking→Retromer Dysfunction→Aβ Accumulation→AD Causal ChainKG

mechanism · 1,688 words · 32 hyp44 ana11 exp

💊 Failed Alzheimer's Disease Clinical Trials AnalysisKG

therapeutic · 1,637 words · 45 hyp31 ana76 exp

🧬 OPRK1 — Kappa Opioid ReceptorKG

gene · 1,627 words · 2 hyp4 ana12 exp

⚙️ Disease Progression Timeline Synthesis — Neurodegenerative Disease Chronological MappingKG

mechanism · 1,596 words · 9 hyp44 ana2 exp

🏢 Therapeutic Approach Evidence RankingsKG

company · 1,579 words · 20 hyp17 ana13 exp

⚙️ Therapeutic Approach Evidence RankingsKG

mechanism · 1,485 words · 32 hyp52 ana20 exp

🧪 EMST with SpiroGym App for Parkinson's Disease (NCT06942533)KG

clinical · 1,440 words · 3 hyp15 ana59 exp

Quantitative Susceptibility Mapping for Corticobasal SyndromeKG

diagnostic · 1,339 words · 28 hyp19 ana1 exp

🔬 Kappa Opioid Receptor (KOR) NeuronsKG

cell · 1,319 words · 9 hyp13 ana12 exp

🔬 Arcuate NPY/AgRP in AppetiteKG

cell · 1,287 words · 5 hyp5 ana

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