| Gene Symbol | OPRK1 |
| Aliases | KOR, OPRK |
| Chromosome | 8q11.23 |
| Protein Type | Receptor |
| Function | Dynorphins are the only known endogenous ligands with significant KOR selectivity; beta-endorphin and enkephalins bind primarily to mu and delta receptors[@bruchas2011]. |
| Primary Expression | CNS (striatum, cortex, hippocampus, hypothalamus, spinal cord), peripheral sensory neurons, immune cells |
| Molecular Weight | ~48 kDa |
| Amino Acids | 426 aa |
| Pathways | MAPK pathway, PI3K |
| UniProt ID | P41145 |
| NCBI Gene ID | 4985 |
| GeneCards | OPRK1 |
| Human Protein Atlas | OPRK1 |
| Protein Name | Kappa-opioid receptor (KOR) |
| Protein Length | 426 amino acids |
| Associated Diseases | Parkinson's disease, Alzheimer's disease |
| Databases | GeneCardsHPASTRING |