gene 3,161 words KG: RNASEK 2026-03-27
kind:genesection:genesstate:published
Contents

RNASEK — Ribonuclease Kappa

🧬 Gene Info
Gene SymbolRNASEK
Full NameRibonuclease Kappa
Chromosome17p11.2
Functionis a gene encoding a cytoplasmic endoribonuclease that degrades circular RNAs (circRNAs).
Subcellular Localization**Primary location**: Cytoplasm
Molecular Weight31.2 kDa
Amino Acids278 aa
Exons8
Gene TypeProtein coding
PathwaysNF-κB
UniProt IDQ9BYX4
NCBI Gene ID124540
Ensembl IDENSG00000166987
OMIM619356
GeneCardsRNASEK
Human Protein AtlasRNASEK
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (20)

Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
APOE-Dependent Autophagy Restoration
Score: 0.61
Senescence-Activated NAD+ Depletion Rescue
Score: 0.60
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59

Related Analyses (3)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived

Related Experiments (5)

Mechanism: C9orf72 Hexanucleotide Repeat Expansion in ALS/FT
validation · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
Microglial Aging and Immune Memory in Neurodegeneration — Tr
validation · proposed · Score: 0.40
Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40
Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in