SciDEX — Wiki (81 pages)

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

Scientific World Model

What is the Scientific World Model?

⚙️ Astrocyte Reactivity MechanismKG

🔬 AstrocytesKG

⚙️ Astrocyte Metabolic Enhancement Therapy for PDKG

🏢 Astrocyte-Targeted Parkinson's Disease Therapy CompaniesKG

⚙️ Astrocyte Reactivity in 4R-TauopathiesKG

⚙️ Astrocyte-Neuron Metabolic Coupling PathwayKG

⚙️ Astrocyte-Mediated NeuroinflammationKG

⚙️ Astrocyte Senescence Pathway in NeurodegenerationKG

🔬 Astrocytes in NeurodegenerationKG

⚙️ PSP Astrocytic Pathology: Tufted Astrocytes MechanismKG

CAR-A Therapy — Chimeric Antigen Receptor Astrocytes for Alzheimer's DiseaseKG

⚙️ Astrocyte Dysfunction in Parkinson's DiseaseKG

🔬 Reactive Astrocytes (A2 Phenotype)KG

💡 Astrocyte Glutamate-Buffer Rescue: EAAT2 Transcription Reboot TherapyKG

📊 Astrocyte-Derived Exosomal mRNA Reference Genes for Alzheimer's DiseaseKG

💊 Astrocyte Metabolic Modulation Therapy for NeurodegenerationKG

Astrocyte-Neuron Metabolic Coupling Hypothesis in Parkinson's DiseaseKG

💡 Astrocyte Glutamate-Buffer Rescue with EAAT2 Transcription RebootKG

🔬 Disease-Associated Astrocytes (DAA)KG

🔬 Astrocytes in Amyotrophic Lateral SclerosisKG

⚙️ Astrocyte Dysfunction: AD vs PD vs ALS vs FTD vs HD ComparisonKG

💡 Astrocyte-to-Neuron Reprogramming TherapyKG

🧫 Astrocyte Ferritin Iron Metabolism Dysfunction in Parkinson's DiseaseKG

🏢 ad-astrocyte-reactivity-companiesKG

🔬 Astrocytes in Brain HomeostasisKG

🔬 Astroglia (Astrocytes)KG

🔬 Perivascular AstrocytesKG

🔬 Synaptic AstrocytesKG

🔬 Nigral AstrocytesKG

🔬 Inflammatory AstrocytesKG

🔬 Locus Coeruleus AstrocytesKG

🔬 Reactive Astrocytes in NeuroinflammationKG

🔬 Protoplasmic AstrocytesKG

💊 astrocyte-modulation-therapyKG

🔬 A1 Reactive AstrocytesKG

⚙️ Astrocyte Iron Metabolism and Alpha-Synuclein Pathology in Parkinson's DiseaseKG

🔬 Aging-Associated AstrocytesKG

🔬 Reactive Astrocytes in NeurodegenerationKG

🔬 Disease-Associated Astrocytes (A1/A2)KG

🔬 Neurotoxic AstrocytesKG

🔬 Senescent AstrocytesKG

astrocyte-neuron-metabolic-coupling-parkinsonsKG

🔬 Neuroprotective AstrocytesKG

🔬 APOE4 Homozygous AstrocytesKG

🔬 Astrocyte Precursor CellsKG

🏢 Astrocyte-Targeted Parkinson's Disease TherapiesKG

🔬 Glial Scar AstrocytesKG

AstrocytesKG

🔬 Spinal Cord Astrocytes in NeurodegenerationKG

🔬 Reactive Astrocytes OverviewKG