SciDEX — Wiki (49 pages)

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

Scientific World Model

What is the Scientific World Model?

🏥 Vascular Cognitive Impairment (VCI)KG

💊 cognitive-reserve-cbs-pspKG

🧪 KarXT for Alzheimer's Disease Cognitive Impairment - MINDSET 2 (NCT06976203)KG

🧪 Genistein for Mild Cognitive Impairment (NCT07385937)KG

⚙️ Cognitive Reserve and Resilience in NeurodegenerationKG

Cognitive and Neuropsychiatric Profiles in Corticobasal SyndromeKG

🧪 Cognitive Training to Reduce Incidence of Cognitive Impairment in Older Adults (NCT03848312)KG

🧪 Cognitive and Speech Rehabilitation in CBS (NCT05823421)KG

🧫 Cognitive Reserve Mechanisms in Alzheimer's Disease — Molecular Basis and EnhancementKG

🧫 DLB Cognitive Fluctuation Mechanism ExperimentKG

montreal-cognitive-assessmentKG

💊 Social Engagement and Cognitive Reserve TherapyKG

🧪 KarXT for Alzheimer's Disease Cognitive Impairment - MINDSET 1 (NCT06976216)KG

📊 Speech and Cognitive Biomarkers for Alzheimer's DiseaseKG

Cognitive Assessment Tools for Neurodegenerative DiseasesKG

🏥 Mild Cognitive Impairment (MCI)KG

🏥 HIV-Associated Neurocognitive Disorders (HAND)KG

K-Cardinality Tree (KCT) Network Optimization for DMN Connectivity Analysis in Cognitive DeclineKG

⚙️ APOE Lipid Dysregulation Causal Chain in ADKG

🧪 Botulinum Toxin for CBS-Associated Dystonia (NCT05678901)KG

🏢 Alzheimer's Disease Synaptic Plasticity and Cognitive Enhancement CompaniesKG

AAIC 2026: Cognitive Reserve and Lifestyle InterventionsKG

🧪 Bilingualism Cognitive Reserve AD TrialKG

⚙️ Blood-Brain Barrier Dysfunction in Vascular Cognitive ImpairmentKG

🧪 Theta Deep Brain Stimulation for Cognitive Enhancement in Parkinson's Disease (NCT06518824)KG

⚙️ Cognitive Rehabilitation in Corticobasal SyndromeKG

⚙️ Vascular Cognitive Impairment Mechanistic PathwayKG

ad-cognitive-resilienceKG

⚙️ DLB Cognitive Fluctuation MechanismsKG

🔧 Cognitive Monitoring Brain-Computer Interfaces for NeurodegenerationKG

🏥 Cognitive Impairment in Progressive Supranuclear PalsyKG

🧪 Telephone Cognitive Assessment in PSP (NCT06932809)KG

💊 Cognitive Stimulation and Rehabilitation for Neurodegenerative DiseaseKG

💊 Cognitive Enhancers for NeurodegenerationKG

🏥 Mild Cognitive Impairment (MCI)KG

ADAS-Cog (Alzheimer's Disease Assessment Scale — Cognitive Subscale)KG

🧪 DBS-fMRI Cognitive Decline Study (NCT06960096): Neural Basis for Cognitive Decline Following STN-DBSKG

💊 Cognitive Rehabilitation for Parkinson's DiseaseKG

💊 Cognitive Rehabilitation for Neurodegenerative DiseasesKG

dlb-cognitive-fluctuation-mechanismsKG

💊 Psychosocial Interventions and Cognitive Reserve in CBS/PSPKG

Whole-Body Photobiomodulation for Motor and Cognitive Changes in Parkinson's DiseaseKG

🔬 Cholinergic Neurons in Cognitive DeclineKG

🔬 White Matter Neurons in Vascular Cognitive ImpairmentKG

ADCS-MCI-ADL (Alzheimer's Disease Cooperative Study — Activities of Daily Living, Mild Cognitive Impairment)KG

neuropsychology-cognitive-assessmentKG

💡 Vascular Cognitive Impairment Prevention Bundle for At-Risk Pre-Symptomatic PopulationsKG

AAIC 2026 — Vascular Contributions to Cognitive Impairment and DementiaKG

AAIC 2026 — Vascular Contributions to Cognitive Impairment and DementiaKG