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Clinical: Genistein for Mild Cognitive Impairment (NCT07385937)
clinical
3,822 words
KG: genistein
kind:clinical-trial
section:clinical-trials
state:published
topic:alzheimers
genistein
phytoestrogen
neuroprotection
Contents
Genistein for Mild Cognitive Impairment (NCT07385937)
Knowledge Graph
Related Hypotheses (22)
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.47
Vicious Cycle Hypothesis: Cholinergic Dysfunction Exacerbate
Score: 0.61
Palmitoylation-Targeted BACE1 Trafficking Disruptors
Score: 0.41
Soluble TREM2 (sTREM2) as Therapeutic Mimic — Decoupling Pha
Score: 0.45
TREM2-Dependent Microglial Senescence Transition
Score: 0.69
APOE-Dependent Autophagy Restoration
Score: 0.61
Digital Twin-Guided Metabolic Reprogramming
Score: 0.61
Circadian Clock-Autophagy Synchronization
Score: 0.55
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.52
Temporal Decoupling via Circadian Clock Reset
Score: 0.52
Lysosomal Calcium Channel Modulation Therapy
Score: 0.49
Lysosomal Enzyme Trafficking Correction
Score: 0.49
TREM2-mediated microglial tau clearance enhancement
Score: 0.49
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.48
APOE-TREM2 Interaction Modulation
Score: 0.48
Lysosomal Membrane Repair Enhancement
Score: 0.45
TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.43
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.43
Lysosomal Positioning Dynamics Modulation
Score: 0.43
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.41
The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.40
TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.40
Show 17 more
Related Analyses (2)
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Related Experiments (3)
Cytochrome Therapeutics
clinical · proposed · Score: 0.46
Neural Stem Cell Therapy for Alzheimer's Disease
clinical · proposed · Score: 0.46
Mouse Cdk5, p35, and p39 mutations in neuronal migration
validation · proposed · Score: 0.80
See Also (3)
NRF2 Activator Therapy
idea · KG edge: activates
NRF2 Gene
gene · KG edge: activates
MMP9 Gene
gene · KG edge: interacts_with
Knowledge Graph (1 edges)
genistein
activates
NRF2