SASP Modulation Rather Than Cell Elimination
SDA-2026-04-16-hyp-daadc5c6
## Mechanistic Overview
SASP Modulation Rather Than Cell Elimination starts from the claim that modulating NFKB1,IL1B,BDNF within the disease context of neurodegeneration can redirect a disease-relevant process. The original description reads: "# SASP Modulation Rather Than Cell Elimination
## Hypothesis Expansion: Selectively Modulating the Senescence-Associated Secretory Phenotype Through NF-κB
Elo ratings (across arenas)
| Arena | Rating | RD | W-L-D | N |
|---|---|---|---|---|
| tournament:top50 | 1500 | ±350 | 0-0-0 | 0 |
| global | 1500 | ±350 | 0-0-0 | 0 |
Ancestry (oldest → this)
(no parents — root hypothesis)
Descendants
(no variants yet)