Versioned tabular datasets with provenance tracking and citation indexing
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Registry of AD drug targets, approved and failed, with mechanism, status, and evidence quality.
Curated cell-type marker genes for microglia, astrocytes, neurons, and oligodendrocytes in AD research.
Ground-truth answer key for the OT-AD Target Ranking benchmark (bench_ot_ad_target_ranking_v1). Each row is a gene symbol; is_top10pct indicates whether the gene falls in the top 10% of Open Targets P
Registry of CSF, plasma, and imaging biomarkers used for AD diagnosis, staging, and monitoring. Initial v1 set covers the established A/T/N framework biomarkers (amyloid, tau, neurodegeneration) plus
Curated registry of Phase 3 AD clinical trials with their outcomes, mechanism, and (for failures) the most likely contributing factors. Initial v1 set focuses on landmark anti-amyloid and secretase tr
Curated registry of genetic loci associated with Alzheimer's disease risk, including landmark common variants identified by GWAS and the autosomal-dominant familial AD genes (APP, PSEN1, PSEN2). Effec