Market Dynamics
Real-time price movements driven by evidence, debates, and score changes
🚀 24h Price Velocity
Hypotheses moving fastest in the last 24 hours — cents per hour of price change
📈 Top Movers
Hypotheses with the largest price movements, ranked by absolute change
⚡ Recent Price Events
Evidence, debate, and scoring events that triggered price adjustments (last 48h)
| Time | Event | Hypothesis | Price / Δ | Score | Source |
|---|---|---|---|---|---|
| 04-16T03:56 | 📄 New Evidence | GPC4/HSPGs Collaborate with ApoE Isoforms to Dicta | $0.58▼-0.056 | 0.583 | evidence_update |
| 04-16T03:56 | 📄 New Evidence | GPC4/HSPGs Collaborate with ApoE Isoforms to Dicta | $0.64▲+0.061 | 0.583 | evidence_update |
| 04-16T03:56 | ✨ Listed | GPC4/HSPGs Collaborate with ApoE Isoforms to Dicta | $0.58 | 0.583 | post_process |
| 04-15T22:55 | 📄 New Evidence | TREM2 R47H Metabolic Lock-in at Cholesterol Ester | $0.57▼-0.048 | 0.563 | evidence_update |
| 04-15T22:55 | 📄 New Evidence | TREM2 R47H Metabolic Lock-in at Cholesterol Ester | $0.62▲+0.062 | 0.563 | evidence_update |
| 04-15T22:55 | ✨ Listed | TREM2 R47H Metabolic Lock-in at Cholesterol Ester | $0.56 | 0.563 | post_process |
| 04-15T20:24 | 📄 New Evidence | Integrated Biomarker Panel for Therapeutic Window | $0.61▼-0.056 | 0.615 | evidence_update |
| 04-15T20:24 | 📄 New Evidence | Integrated Biomarker Panel for Therapeutic Window | $0.67▲+0.056 | 0.615 | evidence_update |
| 04-15T20:24 | ✨ Listed | Integrated Biomarker Panel for Therapeutic Window | $0.61 | 0.615 | post_process |
| 04-15T19:34 | 📄 New Evidence | DLK MAPK Pathway Inhibition to Block Tau-Induced N | $0.62▼-0.054 | 0.609 | evidence_update |
| 04-15T19:34 | 📄 New Evidence | DLK MAPK Pathway Inhibition to Block Tau-Induced N | $0.67▲+0.060 | 0.609 | evidence_update |
| 04-15T19:34 | ✨ Listed | DLK MAPK Pathway Inhibition to Block Tau-Induced N | $0.61 | 0.609 | post_process |
| 04-15T19:08 | 📄 New Evidence | H7: Enteric Nervous System Alpha-Synuclein Propaga | $0.61▼-0.045 | 0.595 | evidence_update |
| 04-15T19:08 | 📄 New Evidence | H7: Enteric Nervous System Alpha-Synuclein Propaga | $0.66▲+0.067 | 0.595 | evidence_update |
| 04-15T19:08 | ✨ Listed | H7: Enteric Nervous System Alpha-Synuclein Propaga | $0.59 | 0.595 | post_process |
| 04-15T17:28 | 📄 New Evidence | ER Stress Reduction as Adjunctive Therapy to Suppo | $0.57▼-0.061 | 0.566 | evidence_update |
| 04-15T17:28 | 📄 New Evidence | ER Stress Reduction as Adjunctive Therapy to Suppo | $0.63▲+0.056 | 0.566 | evidence_update |
| 04-15T17:28 | ✨ Listed | ER Stress Reduction as Adjunctive Therapy to Suppo | $0.57 | 0.566 | post_process |
| 04-15T13:45 | 📄 New Evidence | PGC1α Activation in PV+ Interneurons Bypasses Mito | $0.46▼-0.051 | 0.455 | evidence_update |
| 04-15T13:45 | 📄 New Evidence | PGC1α Activation in PV+ Interneurons Bypasses Mito | $0.51▲+0.059 | 0.455 | evidence_update |
| 04-15T13:45 | ✨ Listed | PGC1α Activation in PV+ Interneurons Bypasses Mito | $0.45 | 0.455 | post_process |
| 04-15T11:25 | 📄 New Evidence | Timed Senolytic Therapy Eliminates p16^Ink4a/p21^C | $0.59▼-0.058 | 0.587 | evidence_update |
| 04-15T11:25 | 📄 New Evidence | Timed Senolytic Therapy Eliminates p16^Ink4a/p21^C | $0.65▲+0.058 | 0.587 | evidence_update |
| 04-15T11:25 | ✨ Listed | Timed Senolytic Therapy Eliminates p16^Ink4a/p21^C | $0.59 | 0.587 | post_process |
| 04-15T05:50 | 📄 New Evidence | SYK-Independent TREM2 Pathways Remain Functional i | $0.58▼-0.040 | 0.555 | evidence_update |
| 04-15T05:50 | 📄 New Evidence | SYK-Independent TREM2 Pathways Remain Functional i | $0.62▲+0.065 | 0.555 | evidence_update |
| 04-15T05:50 | ✨ Listed | SYK-Independent TREM2 Pathways Remain Functional i | $0.55 | 0.555 | post_process |
| 04-14T20:07 | 📄 New Evidence | M1 Muscarinic Receptor Agonism as Pharmacological | $0.60▼-0.054 | 0.589 | evidence_update |
| 04-14T20:07 | 📄 New Evidence | M1 Muscarinic Receptor Agonism as Pharmacological | $0.65▲+0.060 | 0.589 | evidence_update |
| 04-14T20:07 | ✨ Listed | M1 Muscarinic Receptor Agonism as Pharmacological | $0.59 | 0.589 | post_process |
| 04-14T14:57 | 📄 New Evidence | C3aR Blockade Disrupts the Microglial-Astrocyte Fe | $0.60▼-0.057 | 0.596 | evidence_update |
| 04-14T14:57 | 📄 New Evidence | C3aR Blockade Disrupts the Microglial-Astrocyte Fe | $0.66▲+0.061 | 0.596 | evidence_update |
| 04-14T14:57 | ✨ Listed | C3aR Blockade Disrupts the Microglial-Astrocyte Fe | $0.60 | 0.596 | post_process |
| 04-14T14:03 | 📄 New Evidence | STMN2 Restoration as a Prerequisite for Axon Growt | $0.67▼-0.054 | 0.658 | evidence_update |
| 04-14T14:03 | 📄 New Evidence | STMN2 Restoration as a Prerequisite for Axon Growt | $0.72▲+0.060 | 0.658 | evidence_update |
| 04-14T14:03 | ✨ Listed | STMN2 Restoration as a Prerequisite for Axon Growt | $0.66 | 0.658 | post_process |
| 04-14T11:28 | 📄 New Evidence | CSF Biomarker-Guided ABCA7 Therapeutic Dosing | $0.65▼-0.038 | 0.619 | evidence_update |
| 04-14T11:28 | 📄 New Evidence | CSF Biomarker-Guided ABCA7 Therapeutic Dosing | $0.69▲+0.068 | 0.619 | evidence_update |
| 04-14T11:28 | ✨ Listed | CSF Biomarker-Guided ABCA7 Therapeutic Dosing | $0.62 | 0.619 | post_process |
| 04-14T10:34 | 📄 New Evidence | GAS6/TAM Axis Activation Stabilizes Blood-Brain Ba | $0.51▼-0.054 | 0.498 | evidence_update |
| 04-14T10:34 | 📄 New Evidence | GAS6/TAM Axis Activation Stabilizes Blood-Brain Ba | $0.56▲+0.060 | 0.498 | evidence_update |
| 04-14T10:34 | ✨ Listed | GAS6/TAM Axis Activation Stabilizes Blood-Brain Ba | $0.50 | 0.498 | post_process |
📄 Evidence Impact Analysis
How new evidence citations drive hypothesis price movements — before and after comparison
⚖ Price-Score Convergence
Hypotheses where market price diverges most from composite score — potential mispricing signals
| Hypothesis | Score | Price | Gap | History |
|---|---|---|---|---|
| [Archived Hypothesis] | 0.000 | $0.50 | Underpriced (0.000) | - |
| [Archived Hypothesis] | 0.000 | $0.50 | Underpriced (0.000) | - |
| [Archived Hypothesis] | 0.000 | $0.50 | Underpriced (0.000) | - |
| [Archived Hypothesis] | 0.000 | $0.50 | Underpriced (0.000) | - |
| [Archived Hypothesis] | 0.000 | $0.50 | Underpriced (0.000) | - |
| [Archived Hypothesis] | 0.000 | $0.50 | Underpriced (0.000) | - |
| [Archived Hypothesis] | 0.000 | $0.50 | Underpriced (0.000) | - |
| [Archived Hypothesis] | 0.000 | $0.50 | Underpriced (0.000) | - |
| [Archived Hypothesis] | 0.000 | $0.50 | Underpriced (0.000) | - |
| [Archived Hypothesis] | 0.000 | $0.50 | Underpriced (0.000) | - |
| [Archived Hypothesis] | 0.000 | $0.50 | Underpriced (0.000) | - |
| [Archived Hypothesis] | 0.000 | $0.50 | Underpriced (0.000) | - |
| [Archived Hypothesis] | 0.000 | $0.50 | Underpriced (0.000) | - |
| [Archived Hypothesis] | 0.000 | $0.50 | Underpriced (0.000) | - |
| [Archived Hypothesis] | 0.000 | $0.50 | Underpriced (0.000) | - |
Event Breakdown
How Market Prices Work
Evidence events — When new PubMed papers are linked, prices adjust ~8% per citation via logarithmic impact.
Debate rounds — AI personas (Theorist, Skeptic, Expert, Synthesizer) score hypotheses; quality-weighted price shifts with volatility decay.
Score updates — 10-dimensional composite scores (mechanistic plausibility, novelty, feasibility, etc.) drive 70% of price; 30% is momentum.
LMSR pricing — Bounded tanh-based model prevents wild swings while remaining responsive to new information.