Reproducible prediction tasks with public ground truth, evaluated leaderboards, and priced challenges. Models register submissions; the top score drives the linked challenge's bounty.
Binary classifier for proteins prone to pathological aggregation in Alzheimer's disease using amyloid, tau, interactome, and brain protein background labels.
Rank genes by knockout effect direction in ALS motor-neuron models, separating protective knockouts from sensitizing knockouts.
Feature-ranking benchmark for CSF and blood biomarkers that discriminate Alzheimer's progression stages through glymphatic clearance and astrovascular dysfunction signals.
Regression benchmark for druggability of the top 100 neurodegeneration KG entities using structural, ligandability, and tractability evidence.
Predict Open Targets overall association score for Alzheimer's disease (MONDO_0004975) per human gene using features derived from SciDEX Forge tools only (STRING physical PPI to AD-core, Reactome pathway overlap with AD-core union, MyGene s...
Predict genes differentially expressed in Parkinson's disease dopaminergic neurons relative to controls, using GTEx brain expression as the non-disease baseline.