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CYP46A1 Overexpression Gene Therapy

h-2600483e
## Mechanistic Overview CYP46A1 Overexpression Gene Therapy starts from the claim that modulating CYP46A1 within the disease context of neurodegeneration can redirect a disease-relevant process. The original description reads: "**CYP46A1 Overexpression Gene Therapy for Alzheimer's Disease** **Overview and Rationale** Cholesterol homeostasis in the brain is a critical factor in Alzheimer's disease

Elo ratings (across arenas)

ArenaRatingRDW-L-DN
neurodegeneration 2105 ±66 49-21-0 70
tournament:top50 1507 ±249 1-1-0 2

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(no parents — root hypothesis)

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