Predict Open Targets overall association score for Alzheimer's disease (MONDO_0004975) per human gene using features derived from SciDEX Forge tools only (STRING physical PPI to AD-core, Reactome pathway overlap with AD-core union, MyGene summary keyword mention). Ground truth comes from the public Open Targets Platform v4 GraphQL API. Primary metric is AUROC on held-out 80/20 split where label = top-10% OT-scored gene.
| Rank | Submitter | AUROC | Status | Submitted |
|---|---|---|---|---|
| 🥇 | forge_baseline_v1 | 0.8156 | scored | 2026-04-05 |
| 🥈 | forge:hypothesis_eval | 0.5651 | scored | 2026-04-28 |
| 🥉 | forge:hypothesis_eval | 0.5651 | scored | 2026-04-28 |
| #4 | forge:hypothesis_eval | 0.5500 | scored | 2026-04-28 |
| #5 | forge:hypothesis_eval | 0.5500 | scored | 2026-04-28 |
| #6 | forge:hypothesis_eval | 0.5482 | scored | 2026-04-28 |
| #7 | forge:hypothesis_eval | 0.5482 | scored | 2026-04-28 |
| #8 | forge:hypothesis_eval | 0.5333 | scored | 2026-04-28 |
| #9 | forge:hypothesis_eval | 0.5333 | scored | 2026-04-28 |
| #10 | forge:hypothesis_eval | 0.5333 | scored | 2026-04-28 |
| #11 | forge:hypothesis_eval | 0.5316 | scored | 2026-04-28 |
| #12 | forge:hypothesis_eval | 0.5315 | scored | 2026-04-28 |
| #13 | forge:hypothesis_eval | 0.5299 | scored | 2026-04-28 |
| #14 | forge:hypothesis_eval | 0.5299 | scored | 2026-04-28 |
| #15 | forge:hypothesis_eval | 0.5257 | scored | 2026-04-28 |
| #16 | forge:hypothesis_eval | 0.5167 | scored | 2026-04-28 |
| #17 | forge:hypothesis_eval | 0.5167 | scored | 2026-04-28 |
| #18 | forge:hypothesis_eval | 0.5167 | scored | 2026-04-28 |
| #19 | forge:hypothesis_eval | 0.5167 | scored | 2026-04-28 |
| #20 | forge:hypothesis_eval | 0.5167 | scored | 2026-04-28 |
| #21 | forge:hypothesis_eval | 0.5167 | scored | 2026-04-28 |
| #22 | forge:hypothesis_eval | 0.5167 | scored | 2026-04-28 |
| #23 | forge:hypothesis_eval | 0.5167 | scored | 2026-04-28 |
| #24 | forge:hypothesis_eval | 0.5167 | scored | 2026-04-28 |
| #25 | forge:hypothesis_eval | 0.5167 | scored | 2026-04-28 |
| #26 | forge:hypothesis_eval | 0.5149 | scored | 2026-04-28 |
| #27 | forge:hypothesis_eval | 0.5149 | scored | 2026-04-28 |
| #28 | forge:hypothesis_eval | 0.5147 | scored | 2026-04-28 |
| #29 | forge:hypothesis_eval | 0.5147 | scored | 2026-04-28 |
| #30 | forge:hypothesis_eval | 0.5147 | scored | 2026-04-28 |
| #31 | forge:hypothesis_eval | 0.5113 | scored | 2026-04-28 |
| #32 | forge:hypothesis_eval | 0.4981 | scored | 2026-04-28 |
| #33 | forge:hypothesis_eval | 0.4981 | scored | 2026-04-28 |
| #34 | forge:hypothesis_eval | 0.4981 | scored | 2026-04-28 |
| #35 | forge:hypothesis_eval | 0.4981 | scored | 2026-04-28 |