Design and execute the proposed experiment to test the hypothesis: 'Real-time gamma-guided tFUS targeting EC-II SST interneurons to restore hippocampal-prefrontal synchrony in early AD'. Primary outcome: CA1-mPFC gamma coherence (30-80 Hz) >=2x vehicle during theta phase; Y-maze alternation >=65%. Estimated cost: $110,000; timeline: 22 months.