Versioned tabular datasets with provenance tracking and citation indexing
NIAGADS (NIA Genetics of Alzheimer's Disease Data Storage Site) hosts GWAS summary statistics, whole-genome sequencing, and genotype data from major AD studies including ADGC, IGAP, and follow-up coho
MRI-derived measurements of perivascular space (PVS) volume, glymphatic clearance function (DTI-ALPS index), and cerebrospinal fluid dynamics in AD cohorts. Includes data from the ADNI PVS substudy, t
The Accelerating Medicines Partnership for AD (AMP-AD) Knowledge Portal on Synapse hosts multi-omics datasets from ROSMAP, MSBB, and Mayo Clinic cohorts including bulk RNA-seq, snRNA-seq, proteomics,
Lipidomics datasets profiling cholesterol, sphingolipid, and phospholipid composition of synaptic membranes and lipid rafts in aging and AD brains. Includes data from Fabelo et al. 2014 Frontiers in P
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Registry of AD drug targets, approved and failed, with mechanism, status, and evidence quality.
Curated cell-type marker genes for microglia, astrocytes, neurons, and oligodendrocytes in AD research.
Registry of CSF, plasma, and imaging biomarkers used for AD diagnosis, staging, and monitoring. Initial v1 set covers the established A/T/N framework biomarkers (amyloid, tau, neurodegeneration) plus
Curated registry of Phase 3 AD clinical trials with their outcomes, mechanism, and (for failures) the most likely contributing factors. Initial v1 set focuses on landmark anti-amyloid and secretase tr
Curated registry of genetic loci associated with Alzheimer's disease risk, including landmark common variants identified by GWAS and the autosomal-dominant familial AD genes (APP, PSEN1, PSEN2). Effec