Breast Cancer
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🧠 Top Hypotheses
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Near-infrared light therapy stimulates COX4-dependent mitochondrial motility enhancement
84% yes
💬 2
0.74
· therapeutic
0.70
· mechanistic
0.69
· therapeutic
0.68
· combination
0.66
· combination
0.64
· combination
0.56
· mechanistic
0.55
· combination
0.54
· mechanistic
💬 Debates & Sessions
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🔍 Knowledge Gaps
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What are the downstream molecular targets of CX43-dependent STAT1 signaling that confer chemoresistance?
neuro-oncology
How does CX43-mediated intercellular communication specifically activate STAT1 in this context?
neuro-oncology
Do other chemotherapeutic agents show similar astrocyte-mediated resistance through this pathway?
neuro-oncology
How do natural compounds mechanistically target ferroptosis pathways for breast cancer treatment?
pharmacology
📋 Notebooks & Artifacts
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paper_figure · 2026-04-27
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Extended Data Fig. 5: Validation of concurrent RB1 and BRCA2 LOH in external g BRCA2 WES cohort. ...
paper_figure · 2026-04-27
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paper_figure · 2026-04-27
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paper_figure · 2026-04-27
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paper_figure · 2026-04-21
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paper_figure · 2026-04-21
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