Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about parkinsons-disease: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
flowchart TD
N0["PARKINSONS_DISEASE"]
N1["ALPHA_SYNUCLEIN"]
N1 -->|"associated with"| N0
N2["DOPAMINE_NEURONS"]
N0 -->|"causes"| N2
N3["SNCA"]
N3 -->|"causes"| N0
N4["A53T"]
N4 -->|"causes"| N0
N5["NEURODEGENERATION"]
N5 -->|"contributes to"| N0
N6["ASO"]
N6 -->|"treats"| N0
N7["PLK2_PROTEIN"]
N7 -->|"associated with"| N0
N8["C3"]
N8 -->|"contributes to"| N0
N9["LRRK2"]
N9 -->|"associated with"| N0
N10["PRKN"]
N10 -->|"associated with"| N0
N11["PINK1"]
N11 -->|"associated with"| N0
N12["PARK7"]
N12 -->|"associated with"| N0
N13["MULTIPLE_SCLEROSIS"]
N0 -->|"associated with"| N13
N14["ALZHEIMERS_DISEASE"]
N14 -->|"associated with"| N0
N15["MITOPHAGY"]
N15 -->|"associated with"| N0
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
class N1 protein
class N3 gene
class N4 protein
class N7 protein
class N8 protein
class N9 gene
class N10 gene
class N11 gene
class N12 gene
class N13 disease
class N14 disease
class N15 pathway| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||