ACSL4

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolACSL4
Nameacyl-CoA synthetase long chain family member 4
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the cognitive disabilit

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