gene

adam19

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about adam19: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections

0Hypotheses

0Analyses

1Outgoing

1Incoming

0Experiments

0Debates

No summary available yet. View on Wiki →

🧬 Gene Info

Gene Symbol	ADAM19
Full Name	ADAM metallopeptidase domain 19
Chromosome	5q33.1
Function	is a member of the ADAM family of transmembrane metalloproteinases with important functions in development, neuroprotection, and cellular signaling.
Primary Expression	the heart, skeletal muscle, and nervous system, including brain regions critical for learning and memory
Molecular Weight	105 kDa
Pathways	Notch signaling, Notch
UniProt ID	Q9JIS5
NCBI Gene ID	8748
Ensembl ID	ENSG00000197880
OMIM	604536
GeneCards	ADAM19
Human Protein Atlas	ADAM19
Associated Diseases	Alzheimer's disease through neuregulin signaling pathways:, schizophrenia risk
Databases	GeneCards HPA STRING

🔮 Predicted Structure: adam19 — AlphaFold Q9JIS5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (4)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    A["Regulatory elements"] --> B["adam19 gene"]
    B --> C["mRNA transcript"]
    C --> D["Protein product"]
    D --> E["Cellular function"]
    E --> F["Disease relevance"]
    B --> G["Variant effects"]
    G --> F
    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    class B gene
    class D protein

Outgoing (1)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:ADAM19	data_in	dataset_row	0.00

Incoming (1)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:ADAM19	data_in	dataset_row	0.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity