Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about adgrv1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | ADGRV1 |
| Full Name | ADGRV1 |
| Aliases | GPR98 |
| Protein Type | Gene |
| Function | is a member of the adhesion GPCR family, characterized by a large extracellular N-terminal region containing multiple calx-beta domains and a GPS (GPCR proteolysis site) domain. |
| Primary Expression | the cerebellum, hippocampus, and cerebral cortex, where it may function in synaptic organizatio |
| Subcellular Localization | retinal photoreceptor cells (2017)](https://doi.org/10.1016/j.exer.2017.07.012) |
| Molecular Weight | 690 kDa |
| Amino Acids | 6000 aa |
| NCBI Gene ID | Search NCBI |
| Ensembl ID | ENSG00000164199 |
| GeneCards | ADGRV1 |
| Human Protein Atlas | ADGRV1 |
| Associated Diseases | epilepsy and autism spectrum disorder |
| Databases | GeneCardsUniProtHPASTRING |
Knowledge base pages for this entity
graph TD
A["Regulatory elements"] --> B["adgrv1 gene"]
B --> C["mRNA transcript"]
C --> D["Protein product"]
D --> E["Cellular function"]
E --> F["Disease relevance"]
B --> G["Variant effects"]
G --> F
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
class B gene
class D protein| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:ADGRV1 | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:ADGRV1 | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity