Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ADORA2A_signaling: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| D2_linked_antidepressant_network_states | modulates | phenotype | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| extracellular_adenosine | activates | process | 0.70 |
| DARPP-32_state | biomarker_for | biomarker | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Parthenolide reduces tonic ADORA2A signaling by lowering inf | 0.659 | neuropharmacology | How does parthenolide specifically modul |
Scientific analyses that reference this entity
neuropharmacology | 2026-04-25 | 4 hypotheses Top: 0.659
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning ADORA2A_signaling in their description or question text
No additional research found