AFDN

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolAFDN
Nameafadin, adherens junction formation factor
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011].

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