AGO1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolAGO1
Nameargonaute RISC component 1
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRN

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