gene

alex1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about alex1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections

0Hypotheses

0Analyses

1Outgoing

1Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	ALEX1
Full Name	ARM Repeat Expressed 1
Chromosome	19p13.3
Function	is a gene encoding a protein with armadillo repeats that is expressed in various tissues, including the brain.
Primary Expression	various tissues, including the brain
Subcellular Localization	ALEX1 localizes primarily to the:
Amino Acids	42 aa
Exons	8
Ensembl ID	ENSG00000141934
GeneCards	ALEX1
Human Protein Atlas	ALEX1
ARM repeats	6-8 armadillo repeats forming a superhelical structure
N-terminal domain	Involved in protein-protein interactions
C-terminal domain	Contains nuclear localization signals
Coiled-coil regions	Mediate dimerization
Associated Diseases	ALS pathogenesis:
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

ALEX1 Gene - ARM Repeat Expressed 1

gene · 2295 words

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Pathway Diagram

graph TD
    A["Regulatory elements"] --> B["alex1 gene"]
    B --> C["mRNA transcript"]
    C --> D["Protein product"]
    D --> E["Cellular function"]
    E --> F["Disease relevance"]
    B --> G["Variant effects"]
    G --> F
    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    class B gene
    class D protein

Outgoing (1)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:ALEX1	data_in	dataset_row	0.00

Incoming (1)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:ALEX1	data_in	dataset_row	0.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning alex1 in their description or question text

No additional research found