ALK

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolALK
NameALK receptor tyrosine kinase
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cel

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This is an externally resolved entity

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