AMBRA1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolAMBRA1
Nameautophagy and beclin 1 regulator 1
Typeprotein-coding
Sourcemygene

Summary

Enables GTPase binding activity and ubiquitin protein ligase binding activity. Involved in macroautophagy; positive regulation of phosphatidylinositol 3-kinase activity; and response to mitochondrial depolarisation. Located in cytosol. Colocalizes with mitochondrion. Biomarker of multiple system atrophy. [provided by Alliance of Genome Resources, Apr 2022]

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This is an externally resolved entity

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