APBB2

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolAPBB2
Nameamyloid beta precursor protein binding family B member 2
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].

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This is an externally resolved entity

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