Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ASOs: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| intron-retained GBA | therapeutic_target_for | mechanism | 0.70 |
| neuronal gene expression | inhibits | mechanism | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| MALAT1 Three-Way Junction as a Druggable Target for Structur | 0.591 | molecular-biology | What are the conserved secondary structu |
| TDP-43 Cryptic Exon–Targeted ASOs to Restore Hippocampal Gam | 0.577 | neurodegeneration | RNA binding protein dysregulation across |
| Sequence-Specific RNA Antisense Oligonucleotides (ASOs) for | 0.000 | - | How do dilncRNAs specifically drive mole |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-26 | 7 hypotheses Top: 0.645
neurodegeneration | 2026-04-02 | 4 hypotheses Top: 0.720
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 1.00 · 2026-04-26
closed · Rounds: 4 · Score: 0.82 · 2026-04-22
Hypotheses and analyses mentioning ASOs in their description or question text
No additional research found