ASXL1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolASXL1
NameASXL transcriptional regulator 1
Typeprotein-coding
Sourcemygene

Summary

This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The prot

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