ATG5

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolATG5
Nameautophagy related 5
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several tra

1675Connections

This is an externally resolved entity

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