ATG7

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolATG7
Nameautophagy related 7
Typeprotein-coding
Sourcemygene

Summary

This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, S

1420Connections

This is an externally resolved entity

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