AURKC

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolAURKC
Nameaurora kinase C
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provid

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