protein

BCLXLPROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BCLXLPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Bcl Xl Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	BCLXLPROTEIN
Full Name	Bcl-XL (BCL2 Like 1, Isoform 1)
Protein Family	BCL-2 family (BH1-BH4)
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	many tissues including brain, heart, and kidney
Molecular Weight	26 kDa
UniProt ID	Q07817
GeneCards	BCLXLPROTEIN
Human Protein Atlas	BCLXLPROTEIN
BH4 domain	N-terminal amphipathic helix, important for anti-apoptotic function
BH3 domain	Hydrophobic groove for binding pro-apoptotic proteins
BH1 and BH2 domains	Form the hydrophobic pocket that binds BH3 domains
Synaptic protection	Prevents synaptic loss in models of neurodegeneration
Metabolic support	Interacts with mitochondrial proteins to maintain ATP production
Calcium homeostasis	Modulates ER calcium release
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: BCLXLPROTEIN — AlphaFold Q07817 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Bcl-XL Protein

protein · 574 words

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Pathway Diagram

graph TD
    BCLXLPROTEIN["BCLXLPROTEIN"]
    neurodegeneration["neurodegeneration"]
    BCLXLPROTEIN -->|"implicated_in"| neurodegeneration
    style BCLXLPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning BCLXLPROTEIN in their description or question text

No additional research found