GDF10

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolGDF10
Namegrowth differentiation factor 10
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced ex

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