BMPR2

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolBMPR2
Namebone morphogenetic protein receptor type 2
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations i

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