CAPN1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolCAPN1
Namecalpain 1
Typeprotein-coding
Sourcemygene

Summary

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [pr

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