protein

CAV23PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CAV23PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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No summary available yet. View on Wiki →

🔬 Protein Info

Gene Symbol	CAV23PROTEIN
Full Name	Cav2.3 (Voltage-dependent R-type calcium channel subunit α1E)
Protein Family	Voltage-gated calcium channel α1 family (CaV2)
Function	is an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization	Dendritic shafts and spines, cell body
Molecular Weight	~250 kDa (α1 subunit)
UniProt ID	Q15878
GeneCards	CAV23PROTEIN
Human Protein Atlas	CAV23PROTEIN
Protein Name	Cav2.3 (Voltage-dependent R-type calcium channel subunit α1E)
Gene	CACNA1E
PDB Structure	6JPA, 6JPL
Approach	Compound
Direct blocker	SNX-482
Small molecule	Y5AA-311N
Associated Diseases	neurodegeneration
Interactions	TAU, ALZHEIMER, AMYLOID, WAS, CAV2
KG Connections	9 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: CAV23PROTEIN — AlphaFold Q15878 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Cav2.3 Protein

protein · 853 words

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Pathway Diagram

graph TD
    CAV23PROTEIN["CAV23PROTEIN"]
    neurodegeneration["neurodegeneration"]
    CAV23PROTEIN -->|"implicated_in"| neurodegeneration
    style CAV23PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found