Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CAV31PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | CAV31PROTEIN |
| Full Name | Cav3.1 (T-type calcium channel subunit α1G) |
| Protein Family | Voltage-gated calcium channel α1 family (CaV3) |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | Dendrites, cell body, proximal axon |
| Molecular Weight | ~240 kDa |
| UniProt ID | O43497 |
| GeneCards | CAV31PROTEIN |
| Human Protein Atlas | CAV31PROTEIN |
| Protein Name | Cav3.1 (T-type calcium channel subunit α1G) |
| Gene | CACNA1G |
| PDB Structure | 6JPA (channel complex) |
| Approach | Compound |
| Direct blocker | Ethosuximide |
| Broad blocker | Zonisamide |
| Associated Diseases | neurodegeneration |
| Interactions | AMYLOID, ALZHEIMER, CACNA1G, BETA-CATENIN, CAV3, GAIN |
| KG Connections | 25 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
CAV31PROTEIN["CAV31PROTEIN"]
neurodegeneration["neurodegeneration"]
CAV31PROTEIN -->|"implicated_in"| neurodegeneration
style CAV31PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||