gene

CCDC157

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about CCDC157: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for CCDC157 Gene

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🧬 Gene Info

Gene Symbol	CCDC157
Chromosome	6p21.1.
Protein Type	Gene
Function	is a protein-coding gene located on chromosome 6p21.
Primary Expression	various tissues with notable expression in: - Brain: Detected in multiple brain regions including cortex, [hippocampus](/
Subcellular Localization	various cellular compartments, including the cytoskeleton and potentially the nuclear envelope [2](https://doi.org/10.10
UniProt ID	Q8N7H5
NCBI Gene ID	124935
Ensembl ID	ENSG00000160801
GeneCards	CCDC157
Human Protein Atlas	CCDC157
Coiled-coil domains	Multiple predicted coiled-coil regions mediate homotypic and heterotypic protein interactions
Nuclear localization signals	Potential NLS sequences suggest possible nuclear function
Post-translational modifications	Predicted phosphorylation and glycosylation sites
Brain	Detected in multiple brain regions including cortex, hippocampus, and cerebellum
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CCDC157 — AlphaFold Q8N7H5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

CCDC157 Gene

gene · 581 words

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Pathway Diagram

graph TD
    CCDC157["CCDC157"]
    neurodegeneration["neurodegeneration"]
    CCDC157 -->|"implicated_in"| neurodegeneration
    style CCDC157 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning CCDC157 in their description or question text

No additional research found