CD2AP

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolCD2AP
NameCD2 associated protein
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytos

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This is an externally resolved entity

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