Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CD47-BLOCKING ANTIBODY: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | CD47-BLOCKING ANTIBODY |
Knowledge base pages for this entity
graph TD
CD47_BLOCKING_ANTIBODY["CD47-BLOCKING ANTIBODY"]
CD47_BLOCKING_ANTIBODY -->|"inhibits"| Neutrophil_Extracellular_Traps["Neutrophil Extracellular Traps"]
CD47_BLOCKING_ANTIBODY -->|"treats"| Spinal_Cord_Edema["Spinal Cord Edema"]
CD47_BLOCKING_ANTIBODY -->|"suppresses"| Tlr4_Nf__b_Mmp2_Mmp9_Pathway["Tlr4-Nf-Kappab-Mmp2/Mmp9 Pathway"]
CD47_BLOCKING_ANTIBODY -.protects against.-> Blood_Spinal_Cord_Barrier["Blood-Spinal Cord Barrier"]
CD47_BLOCKING_ANTIBODY -.protects against.-> Blood_Spinal_Cord_Barrier_Inte["Blood-Spinal Cord Barrier Integrity"]| Target | Relation | Type | Str |
|---|---|---|---|
| Neutrophil Extracellular Traps | inhibits | process | 0.95 |
| Neutrophil Extracellular Traps Formation | inhibits | process | 0.95 |
| Spinal Cord Edema | associated_with | phenotype | 0.95 |
| Spinal Cord Edema | treats | phenotype | 0.92 |
| Spinal Cord Edema | treats | phenotype | 0.92 |
| Spinal Cord Edema | treats | phenotype | 0.92 |
| Tlr4-Nf-Κb-Mmp2/Mmp9 Pathway | suppresses | pathway | 0.90 |
| Blood-Spinal Cord Barrier | protects_against | process | 0.90 |
| Blood-Spinal Cord Barrier Integrity | protects_against | mechanism | 0.90 |
| TLR4-NFKB1-MMP2/MMP9 pathway | suppresses | pathway | 0.90 |
| Neuronal Death | protects_against | phenotype | 0.88 |
| S100A8/A9 | downregulates | protein | 0.88 |
| S100A8/A9 | downregulates | protein | 0.88 |
| Spinal Cord Injury | therapeutic_target | disease | 0.88 |
| TLR4-NF-κB-MMP2/MMP9 | inhibits | pathway | 0.85 |
| Inflammatory Cell Infiltration | associated_with | process | 0.85 |
| neutrophil infiltration | associated_with | process | 0.85 |
| TLR4-NF-κB-MMP2/MMP9 | inhibits | pathway | 0.82 |
| Neuronal Death | protects_against | phenotype | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||