CD8A

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolCD8A
NameCD8 subunit alpha
Typeprotein-coding
Sourcemygene

Summary

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta

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