Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CDK11A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Gene profile: CDK11A - cyclin-dependent kinase involved in RNA splicing, cell cycle regulation, and neurodegeneration
No AI portrait yet
| Gene Symbol | CDK11A |
| Full Name | Cyclin Dependent Kinase 11A |
| Aliases | Gene profile: CDK11A |
| Chromosome | 1p36.21 |
| Protein Type | Kinase |
| Function | RNA splicing, cell cycle regulation, transcription |
| Primary Expression | Ubiquitous, high in brain |
| Molecular Weight | 92 kDa |
| Amino Acids | 795 aa |
| Exons | 18 |
| UniProt ID | Q9UQ88 |
| NCBI Gene ID | 984 |
| Ensembl ID | ENSG00000089234 |
| OMIM | 176871 |
| GeneCards | CDK11A |
| Human Protein Atlas | CDK11A |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
CDK11A["CDK11A"]
neurodegeneration["neurodegeneration"]
CDK11A -->|"implicated_in"| neurodegeneration
style CDK11A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CDK11A in their description or question text
No additional research found