gene

CHASER

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CHASER: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

CYP11A1 Gene - Cholesterol Side-Chain Cleavage Enzyme

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🧬 Gene Info

Gene Symbol	CYP11A1
Full Name	Cytochrome P450 Family 11 Subfamily A Member 1
Aliases	CHASER, Cholesterol Side-Chain Cleavage Enzyme
Chromosome	15q24.2
Protein Family	Cytochrome P450
Function	Cyp11A1 Protein (Cholesterol Side Chain Cleavage Enzyme) is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, fu...
Subcellular Localization	- functional domains specific to its protein family - potential regulatory regio
Molecular Weight	56 kDa
Pathways	Autophagy, Ubiquitin-Proteasome, epigenetic regulation, oxidative stress response, autophagy pathway
UniProt ID	P05093
NCBI Gene ID	1583
Ensembl ID	ENSG00000140359
OMIM	118485
GeneCards	CYP11A1
Human Protein Atlas	CYP11A1
Interactions	TUBB3, HDAC6, CDC42, MAP3K5, CASP3, GJA1
KG Connections	93 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CHASER — AlphaFold P05093 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (4)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    CHASER["CHASER"]
    neurodegeneration["neurodegeneration"]
    CHASER -->|"implicated_in"| neurodegeneration
    style CHASER fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found